Lanzol Junior : Usage, Benefits, and Precautions

Introduction to Lanzol Junior

Lanzol Junior by Cipla is a widely used medication for treating acid-related disorders in children.

It contains Lansoprazole, a proton pump inhibitor (PPI) that helps reduce stomach acid production. This medicine is commonly prescribed for conditions like acid reflux, gastritis, and peptic ulcers in children.

Understanding how Lanzol Junior works, its benefits, possible side effects, and precautions is crucial for parents and caregivers. In this guide, we’ll cover all the essential details you need to know before using Lanzol Junior.

Composition of Lanzol Junior

Lansoprazole (15 mg or 30 mg)

Oral Forms of Lanzol Junior

Dispersible tablets: 15 mg or 30 mg lansoprazole, designed to be dispersed in water before administration.

Oral suspension: A liquid formulation containing 15 mg or 30 mg lansoprazole per 5 mL.

Brands of Lansoprazole kids (Lanzol Junior) available in India(Substitutes)

Lanzoprax Kid by Sun Pharma: This brand is available in two strengths, 15mg and 30mg.

Pan Junior by Panacea Biotec: This brand is available in a strip of 10 tablets.

Lansojoy by Mankind Pharma: This brand is available in two strengths, 15mg and 30mg.

Aprazol by Cipla: This brand is available in two strengths, 0.25mg and 0.5mg.

Lesozap by Lupin:

Luxet Plus by Ranbaxy:

Zopra by Cadila Pharmaceuticals:

Lanfil by FDC:

BestoLee by Bestochem Formulations (I) Ltd.:

Please note that prices may vary depending on the seller and location. It's always best to consult a healthcare professional before switching to a different brand.

Mode of Action of Lanzol Junior

Lanzol Junior contains Lansoprazole, which belongs to the class of proton pump inhibitors (PPIs). It works by blocking an enzyme called H+/K+ ATPase, which is responsible for acid secretion in the stomach. By inhibiting this enzyme, Lanzol Junior significantly reduces acid production, providing relief from symptoms like heartburn, stomach pain, and acid regurgitation.

This mechanism helps in healing stomach ulcers, preventing acid-related damage to the esophagus, and improving digestion in children suffering from gastroesophageal reflux disease (GERD) and other acid-related disorders.

Indications: When is Lanzol Junior Prescribed?

Indications: When is Lanzol Junior Prescribed?

Lanzol Junior (Lansoprazole) is a proton pump inhibitor (PPI) commonly prescribed for pediatric patients suffering from various gastric conditions. It works by reducing the production of stomach acid, thereby alleviating symptoms and promoting healing in acid-related disorders. Below are the primary indications for its use:

1. Gastroesophageal Reflux Disease (GERD)

GERD is a chronic condition in which stomach acid frequently flows back into the esophagus, leading to irritation, inflammation, and discomfort. In children, GERD can present with symptoms such as:

Frequent vomiting or regurgitation

Heartburn (burning sensation in the chest)

Persistent cough or wheezing

Difficulty swallowing

Poor weight gain due to feeding difficulties

Lanzol Junior helps manage GERD by reducing acid production, thereby decreasing irritation and promoting esophageal healing.

2. Peptic Ulcers

Peptic ulcers are open sores that develop on the inner lining of the stomach (gastric ulcers) or the small intestine (duodenal ulcers). They are primarily caused by:

Excessive stomach acid production

Helicobacter pylori (H. pylori) bacterial infection

Prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs)

Symptoms of peptic ulcers in children may include:

Burning or gnawing abdominal pain (often worsening at night or on an empty stomach)

Nausea or vomiting

Loss of appetite

Blood in vomit (hematemesis) or dark, tarry stools (melena)

Lanzol Junior aids in the healing of ulcers by significantly lowering stomach acid levels, allowing the damaged tissue to recover. It is often prescribed in combination with antibiotics if H. pylori is the underlying cause.

3. Erosive Esophagitis

Erosive esophagitis occurs when the esophageal lining is damaged due to prolonged acid exposure. It can result in:

Painful swallowing

Chest pain

Chronic sore throat

Bleeding from the esophagus in severe cases

Lanzol Junior helps in healing erosions by reducing acid production, preventing further irritation, and allowing the esophagus to repair itself.

4. Zollinger-Ellison Syndrome

Zollinger-Ellison Syndrome (ZES) is a rare disorder characterized by the formation of gastrin-secreting tumors (gastrinomas) in the pancreas or duodenum. These tumors cause excessive stomach acid production, leading to severe peptic ulcers and complications such as:

Persistent diarrhea

Intense abdominal pain

Gastrointestinal bleeding

Lanzol Junior is used to control acid hypersecretion in ZES, helping to reduce ulcer formation and related symptoms.

5. H. Pylori Infection (as part of Combination Therapy)

H. pylori is a bacterium that can colonize the stomach lining, leading to inflammation, ulcers, and an increased risk of stomach cancer. In pediatric patients, H. pylori infection may present with:

• Recurrent stomach pain

• Bloating

• Nausea

• Vomiting

Lanzol Junior is used in combination with antibiotics (such as amoxicillin and clarithromycin) to eradicate the bacteria and reduce acid levels, promoting ulcer healing.

6. Dyspepsia (Indigestion)

Dyspepsia, or indigestion, is a common condition in children that results in discomfort and pain in the upper abdomen. Symptoms may include:

Bloating

Nausea

Early satiety (feeling full quickly)

Acidic taste in the mouth

Lanzol Junior helps relieve dyspepsia by controlling excess stomach acid, reducing irritation, and improving digestion.

Lanzol Junior is a well-tolerated and effective medication for managing various acid-related gastrointestinal conditions in children.

It provides symptom relief, promotes healing, and prevents complications associated with excessive stomach acid production.

However, it should only be used under medical supervision, with the appropriate dosage and duration tailored to the child’s specific condition.

Side Effects of Lanzol Junior

Like any medication, Lanzol Junior may cause some side effects. Most of these are mild and go away as the body adjusts to the medication. However, it is important to be aware of them:

Common Side Effects:

Nausea

Headache

Diarrhea or Constipation

Abdominal Pain

Dizziness

Fatigue

Rare but Serious Side Effects:

Severe Allergic Reactions (rash, swelling, difficulty breathing)

Low Magnesium Levels (leading to muscle cramps, irregular heartbeat)

Clostridium difficile Infection (a type of severe diarrhea)

Bone Fractures (with long-term use)

If your child experiences any severe or unusual symptoms, seek medical help immediately.

Contraindications: Who Should Avoid Lanzol Junior?

Lanzol Junior is not suitable for everyone. It should be avoided in the following cases:

Allergy to Lansoprazole or Other PPIs – If your child has a known allergy to any of the ingredients in Lanzol Junior, avoid its use.

Severe Liver Disease – Since the liver processes this drug, children with severe liver impairment should use it cautiously.

Osteoporosis or Bone Disorders – Long-term use of PPIs may increase the risk of fractures.

Low Magnesium Levels – If your child has pre-existing low magnesium levels, the medication can further lower them, leading to complications.

Not Recommended for Newborns – Lanzol Junior is generally prescribed for children, but dosage and suitability must be confirmed by a pediatrician.

Pharmacokinetics of Lanzol Junior (Lansoprazole)

Absorption

Oral bioavailability: 80-90%

Peak plasma concentration (Tmax): 1.5-3.5 hours

Food effect: Delayed absorption, but no significant effect on bioavailability

Distribution

Volume of distribution (Vd): 0.5-1.5 L/kg

Protein binding: 97-99% bound to plasma proteins

Metabolism

Metabolic pathway: Primarily metabolized by CYP2C19 and CYP3A4 in the liver

Major metabolites: 5-hydroxylansoprazole, lansoprazole sulfone

Excretion

Renal excretion: 20-30% of the dose is excreted unchanged in the urine

Fecal excretion: 50-60% of the dose is excreted in the feces

Elimination half-life (t1/2): 1.5-2.5 hours

Special Populations

Pediatric patients: Pharmacokinetics similar to adults

Geriatric patients: Reduced clearance, increased half-life

Hepatic impairment: Reduced clearance, increased half-life

Renal impairment: No significant effect on pharmacokinetics

Precautions for Using Lanzol Junior

Lanzol Junior (Lansoprazole) is a widely used medication for pediatric gastric conditions, but it should be used with caution to ensure safety and effectiveness. Below are the key precautions to keep in mind:

1. Use Only Under Medical Supervision

Lanzol Junior should only be given to children if prescribed by a doctor.

The dosage and duration should be strictly followed as per medical advice.

2. Do Not Crush or Chew the Medication

The granules or capsules should be swallowed whole or mixed with water/soft food as instructed.

Crushing or chewing can affect its effectiveness.

3. Take on an Empty Stomach

It is best taken before meals, preferably in the morning, for optimal absorption.

4. Monitor for Side Effects

Common side effects include nausea, diarrhea, constipation, headache, and stomach pain.

If severe symptoms like allergic reactions, severe diarrhea, or unusual fatigue occur, consult a doctor immediately.

5. Avoid Long-Term Use Without Supervision

Prolonged use can lead to:

Vitamin B12 deficiency

Calcium and magnesium depletion, increasing the risk of weak bones

Rebound acid secretion if stopped abruptly

Regular medical monitoring is necessary for long-term treatment.

6. Watch for Drug Interactions

Lanzol Junior may interact with other medications, such as:

Antibiotics (clarithromycin, amoxicillin) – often used in combination therapy for H. pylori infections.

Antacids – may interfere with absorption; consult a doctor before combining.

Blood thinners (warfarin) – may increase bleeding risk.

Iron supplements – may have reduced absorption with prolonged PPI use.

7. Avoid Certain Foods That Worsen Acid Reflux

Spicy, fatty, fried, and acidic foods should be minimized.

Caffeinated and carbonated drinks can increase acid production.

8. Use with Caution in Children with Liver or Kidney Issues

Dose adjustments may be necessary for children with impaired liver or kidney function.

9. Be Cautious When Stopping the Medication

Do not discontinue Lanzol Junior abruptly, as it may cause a rebound increase in stomach acid.

The doctor may suggest a gradual reduction in dosage before stopping completely.

10. Store Properly

Keep the medication in a cool, dry place, away from direct sunlight and moisture.

Ensure it is stored out of reach of children to prevent accidental overdose.

By following these precautions, Lanzol Junior can be used safely and effectively to treat pediatric gastric conditions.

Always consult a doctor for any concerns regarding its use.

Clinical USP (Unique Selling Points) of Lanzol Junior

Lanzol Junior stands out due to several clinical advantages:

Kid-Friendly Formulation – It comes in dispersible tablets, making it easy to administer to children who have trouble swallowing pills.

Fast-Acting Relief – Works within one hour to reduce stomach acid and provide symptom relief.

Long-Lasting Effect – A single dose provides relief for up to 24 hours, ensuring better symptom control.

Proven Safety Profile – Extensively tested and approved for pediatric use under medical supervision.

Effective in H. pylori Eradication – When combined with antibiotics, it helps treat H. pylori infections efficiently, preventing ulcers from recurring.

Lanzol Junior is an effective and safe medication for treating acid-related stomach disorders in children.

Its ability to reduce stomach acid and promote healing makes it a go-to option for pediatric GERD, ulcers, and indigestion.

However, it should always be used under a doctor's guidance to avoid side effects and complications.

If your child is experiencing acid reflux or other digestive issues, consult a pediatrician to see if Lanzol Junior is the right choice.

Always follow the prescribed dosage and keep an eye out for any unusual symptoms to ensure safe and effective treatment.

Disclaimer: This article is for informational purposes only and should not replace medical advice. Always consult your pediatrician before starting any new medication.

Frequently Asked Questions (FAQs) About Lanzol Junior

1. Can Lanzol Junior be given daily?

Yes, but only as prescribed by a doctor. Long-term use should be monitored to avoid potential side effects.

2. How long does it take for Lanzol Junior to work?

It starts reducing stomach acid within one hour, but full benefits may take a few days to become noticeable.

3. Can Lanzol Junior be used for infants?

Lanzol Junior is generally prescribed for children, but its use in infants should be strictly under a doctor’s guidance.

4. What foods should my child avoid while taking Lanzol Junior?

Spicy, acidic, and fatty foods should be avoided, as they can worsen acid reflux symptoms.

5. Is Lanzol Junior safe for long-term use?

It can be used long-term under medical supervision, but prolonged use may require monitoring for side effects like bone weakness and nutrient deficiencies.

6. How should Lanzol Junior be taken?

It should be taken before meals, usually in the morning. The granules can be mixed with water or soft food if needed.

7. Can Lanzol Junior be taken with other medications?

Some medications may interact with Lanzol Junior, so always inform your doctor about any other medicines your child is taking.

8. What should I do if my child misses a dose?

Give the missed dose as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose—do not double up.

9. Are there any common side effects of Lanzol Junior?

Possible side effects include nausea, diarrhea, stomach pain, headache, and constipation. If severe reactions occur, consult a doctor.

10. Can Lanzol Junior cause vitamin deficiencies?

Long-term use may reduce the absorption of certain nutrients, such as vitamin B12, calcium, and magnesium. Regular monitoring may be needed.

11. Can Lanzol Junior be stopped suddenly?

Stopping suddenly may lead to rebound acid production. Always consult a doctor before discontinuing the medication.

12. Is Lanzol Junior available over the counter?

No, it requires a doctor’s prescription for safe and effective use.

13. Can Lanzol Junior help with nausea and vomiting?

It may help if nausea is caused by acid reflux, but it is not a general anti-nausea medication.

14. Does Lanzol Junior affect appetite?

Some children may experience changes in appetite, though this is not very common.

15. Can Lanzol Junior be used for stomach infections?

It is sometimes used in combination with antibiotics to treat H. pylori infections but is not an antibiotic itself.

16. How long can my child take Lanzol Junior?

The duration depends on the condition being treated. Short courses (2–8 weeks) are common, but longer treatment may be required in some cases under medical supervision.

17. Can Lanzol Junior cause drowsiness?

Drowsiness is not a common side effect, but some children may feel fatigued while taking it.

18. Does Lanzol Junior need to be stored in a specific way?

Store it in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children.

19. Can Lanzol Junior be given with milk?

It is best taken with water. Consult your doctor before mixing it with milk or other beverages.

20. Is Lanzol Junior suitable for children with kidney or liver disease?

Dose adjustments may be needed for children with liver or kidney issues. A doctor should evaluate its safety in such cases.