Allegra 120: Uses, Dosage, Side Effects, and Precautions

Are you tired of living with annoying allergy symptoms? Do you struggle with sneezing, runny nose, and itchy eyes every time the pollen count rises?

Look no further than Allegra 120, a fast-acting and effective antihistamine medication designed to provide long-lasting relief from allergy symptoms.

What is Allegra 120?

Allegra 120, also known as Fexofenadine, is a non-drowsy antihistamine medication that works by blocking the action of histamine, a chemical released by the body's immune system during an allergic reaction.

By blocking histamine, Allegra 120 helps to alleviate symptoms such as sneezing, runny nose, itchy eyes, and skin rashes.

Key Benefits of Allegra 120

Fast-acting relief from allergy symptoms

Long-lasting effects, providing relief for up to 24 hours

Non-drowsy formula, allowing you to stay active and focused

Effective against a range of allergens, including pollen, dust mites, and pet dander

In this article, we'll take a closer look at Allegra 120, its benefits, and how it can help you take control of your allergy symptoms. Whether you're looking for a reliable solution for seasonal allergies or year-round relief, Allegra 120 is definitely worth considering.

Mode of Action of Allegra 120 (Fexofenadine):

Allegra 120, also known as Fexofenadine, is a non-sedating antihistamine medication that provides relief from allergy symptoms. Its mode of action involves a complex process that ultimately leads to the alleviation of allergic reactions. Here's a detailed explanation of how Allegra 120 works:

Histamine Release and Allergic Reactions

When an allergen enters the body, it triggers the release of histamine from mast cells, a type of immune system cell. Histamine is a chemical mediator that plays a key role in the allergic response. It binds to histamine receptors on various cells, leading to a range of symptoms, including:

Increased blood vessel permeability, leading to swelling and edema

Smooth muscle contraction, resulting in bronchospasm and increased mucus production

Stimulation of nerve endings, causing itching, sneezing, and coughing

Mechanism of Action of Fexofenadine

Fexofenadine, the active ingredient in Allegra 120, is a selective histamine H1-receptor antagonist. Its mechanism of action involves:

1. Blocking Histamine Receptors: Fexofenadine binds to histamine H1-receptors on the surface of cells, preventing histamine from binding and triggering an allergic response.

2. Inhibiting Histamine-Mediated Responses: By blocking histamine receptors, Fexofenadine inhibits the histamine-mediated responses that lead to allergic symptoms, such as increased blood vessel permeability, smooth muscle contraction, and nerve stimulation.

3. Reducing Inflammation: Fexofenadine also has anti-inflammatory properties, which help to reduce the inflammation associated with allergic reactions.

Pharmacokinetics and Pharmacodynamics

Fexofenadine is rapidly absorbed after oral administration, with peak plasma concentrations reached within 1-2 hours. It is highly bound to plasma proteins and has a half-life of approximately 14 hours.

The pharmacodynamic effects of Fexofenadine are evident within 1 hour of administration, with maximum effects observed at 2-4 hours. The duration of action is approximately 24 hours, allowing for once-daily dosing.

Clinical Implications

The mode of action of Allegra 120 (Fexofenadine) makes it an effective treatment for a range of allergic conditions, including:

Seasonal allergic rhinitis

Perennial allergic rhinitis

Chronic idiopathic urticaria

Its non-sedating properties and lack of significant interactions with other medications make it a popular choice for patients with allergies.

Uses or Indications of Allegra 120 (Fexofenadine)

Allegra 120, containing the active ingredient Fexofenadine, is indicated for the relief of symptoms associated with various allergic conditions. Here are the specific indications for Allegra 120:

Allergic Rhinitis

1. Seasonal Allergic Rhinitis: Allegra 120 is indicated for the relief of symptoms such as sneezing, runny nose, itchy nose, and congestion associated with seasonal allergic rhinitis (hay fever).

2. Perennial Allergic Rhinitis: It is also indicated for the relief of symptoms associated with perennial allergic rhinitis, including sneezing, runny nose, itchy nose, and congestion.

Urticaria

1. Chronic Idiopathic Urticaria: Allegra 120 is indicated for the relief of symptoms associated with chronic idiopathic urticaria, including itching, redness, and hives.

Allegra 120 for Skin Allergy: Uses, Benefits, and Precautions

Allegra 120, containing the active ingredient Fexofenadine, is an antihistamine medication commonly used to treat various allergic conditions, including skin allergies. Here's a detailed overview of using Allegra 120 for skin allergy:

Types of Skin Allergies Treated with Allegra 120

1. Urticaria: Allegra 120 is effective in treating chronic idiopathic urticaria, characterized by itchy, raised hives on the skin.

2. Atopic Dermatitis: It can also be used to treat atopic dermatitis, a type of eczema characterized by dry, itchy, and inflamed skin.

3. Contact Dermatitis: Allegra 120 may be prescribed to treat contact dermatitis, a skin reaction caused by exposure to allergens or irritants.

Benefits of Using Allegra 120 for Skin Allergy

1. Relieves Itching and Redness: Allegra 120 helps to alleviate itching, redness, and inflammation associated with skin allergies.

2. Reduces Hives and Rashes: It effectively reduces the appearance of hives and rashes, making it an excellent treatment option for urticaria and other skin allergies.

3. Non-Sedating: Unlike some other antihistamines, Allegra 120 is non-sedating, making it suitable for daytime use.

4. Quick Relief: Allegra 120 provides quick relief from skin allergy symptoms, usually within 1-2 hours of administration.

Precautions and Contraindications

1. Renal Impairment: Patients with renal impairment should use Allegra 120 with caution and under medical supervision.

2. Hepatic Impairment: Patients with hepatic impairment should also use Allegra 120 with caution and under medical supervision.

3. Pregnancy and Breastfeeding: Allegra 120 should be used during pregnancy and breastfeeding only if the benefits outweigh the risks.

4. Concomitant Medications: Inform your doctor about all medications you're taking, as Allegra 120 may interact with certain medications.

Dosage and Administration of Allegra 120 for Skin Allergy

1. Adults and Children 12 Years and Older:

   The recommended dosage is one tablet (120 mg) once daily.

2. Children 6 to 11 Years:

   The recommended dosage is one tablet (60 mg) twice daily or one tablet (120 mg) once daily.

Consult with a healthcare professional before taking Allegra 120 for skin allergy to discuss the best treatment plan for your specific condition.

Other Indications

1. Allergic Conjunctivitis: Allegra 120 may also be used to relieve symptoms associated with allergic conjunctivitis, including itchy, watery, and red eyes.

Important Considerations

Allegra 120 is not indicated for the treatment of acute bronchospasm or status asthmaticus.

It is not a substitute for epinephrine in the treatment of anaphylaxis.

Patients with a history of hypersensitivity reactions to Fexofenadine or any other ingredient in Allegra 120 should not use this medication.

It's essential to consult with a healthcare professional before taking Allegra 120 to ensure it's the right medication for your specific condition.

Dosage of Allegra 120 (Fexofenadine)

The recommended dosage of Allegra 120 (Fexofenadine) varies depending on the patient's age, weight, and the condition being treated. Here's a detailed explanation of the dosage:

Adults and Children 12 Years and Older

The recommended dosage is one tablet (120 mg) once daily.

Take the tablet with water, and it can be taken with or without food.

Children 6 to 11 Years

The recommended dosage is one tablet (60 mg) twice daily, or one tablet (120 mg) once daily.

Take the tablet with water, and it can be taken with or without food.

Children 2 to 5 Years

The recommended dosage is one tablet (30 mg) twice daily.

Take the tablet with water, and it can be taken with or without food.

Special Populations

Renal Impairment: Patients with renal impairment should start with a dose of 60 mg once daily.

Hepatic Impairment: Patients with hepatic impairment should use Allegra 120 with caution, and the dose should be adjusted based on the patient's response.

Important Considerations

Allegra 120 should be taken at the same time every day to maintain its effectiveness.

Do not exceed the recommended dose, as it will not provide additional benefits and may increase the risk of side effects.

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.

It's essential to consult with a healthcare professional before taking Allegra 120 to ensure the correct dosage and treatment plan for your specific condition.

Allegra 120 (Fexofenadine) Side Effects:

Allegra 120, containing the active ingredient Fexofenadine, is generally well-tolerated. However, like all medications, it can cause side effects, some of which can be serious. Here's a detailed overview of the possible side effects of Allegra 120:

Common Side Effects (≥2% and <10%)

1. Headache: Mild to moderate headaches can occur in some patients.

2. Drowsiness: Although Allegra 120 is non-sedating, some patients may experience drowsiness.

3. Fatigue: Feeling tired or weak can occur in some patients.

4. Dry Mouth: Allegra 120 can cause dryness in the mouth, throat, or nose.

5. Cough: Some patients may experience a cough, which can be mild or severe.

6. Nausea: Mild to moderate nausea can occur in some patients.

7. Diarrhea: Allegra 120 can cause diarrhea, which is usually mild and temporary.

8. Stomach Upset: Some patients may experience stomach upset, including abdominal pain or discomfort.

Less Common Side Effects (≥1% and <2%)

1. Allergic Reactions: Rarely, patients may experience allergic reactions, including anaphylaxis, angioedema, or skin rash.

2. Tachycardia: Some patients may experience a rapid heart rate.

3. Flushing: Allegra 120 can cause flushing, which is usually mild and temporary.

4. Urticaria: Some patients may experience hives or itchy skin.

5. Pruritus: Allegra 120 can cause itching or pruritus.

Rare but Serious Side Effects (<1%)

1. Anaphylaxis: A severe, life-threatening allergic reaction that requires immediate medical attention.

2. Angioedema: A severe swelling of the face, lips, tongue, or throat that can cause difficulty breathing.

3. Seizures: Rarely, patients may experience seizures while taking Allegra 120.

4. Cardiovascular Events: Allegra 120 may increase the risk of cardiovascular events, including heart attack, stroke, or arrhythmias.

Post-Marketing Reports

1. Hepatotoxicity: Rare cases of liver damage or liver failure have been reported.

2. Psychiatric Events: Rare cases of anxiety, depression, or psychosis have been reported.

Important Considerations

1. Inform your doctor: If you experience any side effects, inform your doctor promptly.

2. Monitor your condition: Regularly monitor your condition and report any changes to your doctor.

3. Seek medical attention: If you experience any severe or persistent side effects, seek medical attention immediately.

Contraindications of Allegra 120 (Fexofenadine)

Allegra 120, containing the active ingredient Fexofenadine, is contraindicated in certain conditions and populations. Here are the contraindications:

Absolute Contraindications

1. Hypersensitivity to Fexofenadine: Patients with a known hypersensitivity to Fexofenadine or any of the excipients in Allegra 120 should not take this medication.

2. Severe Renal Impairment: Allegra 120 is contraindicated in patients with severe renal impairment (creatinine clearance < 10 mL/min).

Relative Contraindications

1. Mild to Moderate Renal Impairment: Patients with mild to moderate renal impairment (creatinine clearance 10-50 mL/min) should use Allegra 120 with caution and under medical supervision.

2. Hepatic Impairment: Patients with hepatic impairment should use Allegra 120 with caution and under medical supervision.

3. Pregnancy: Allegra 120 should be used during pregnancy only if the benefits outweigh the risks.

4. Breastfeeding: Allegra 120 should be used with caution during breastfeeding, as it is excreted in human milk.

Special Populations contraindications

1. Pediatric Patients: Allegra 120 is not recommended for children under 6 years of age.

2. Geriatric Patients: Allegra 120 should be used with caution in geriatric patients, as they may be more susceptible to adverse effects.

Drug Interactions

1. Ketoconazole: Concomitant use of Allegra 120 with ketoconazole can increase Fexofenadine plasma concentrations.

2. Erythromycin: Concomitant use of Allegra 120 with erythromycin can increase Fexofenadine plasma concentrations.

3. Antacids: Concomitant use of Allegra 120 with antacids can decrease Fexofenadine bioavailability.

It's essential to consult with a healthcare professional before taking Allegra 120 to discuss the potential benefits and risks of treatment, especially if you have any underlying medical conditions or take other medications.

FAQ (Frequently Asked Questions) of Allegra 120

Here are the answers to your questions about Allegra:

Can Allegra be used for cough?

Allegra is primarily used to treat allergy symptoms such as itching, sneezing, and runny nose. While it may provide some relief from coughs associated with allergies, it's not a primary treatment for coughs. If you have a persistent cough, consult your doctor for proper diagnosis and treatment.

Is Allegra 120 better than cetirizine?

Both Allegra 120 and cetirizine are effective antihistamines. However, Allegra 120 is considered non-sedating, whereas cetirizine can cause drowsiness in some individuals. Allegra 120 also has a longer duration of action, providing relief for up to 24 hours. Ultimately, the better option depends on your individual needs and preferences. Consult your doctor for personalized advice.

How many Allegra 120 can I take in a day?

The recommended dosage of Allegra 120 is one tablet (120 mg) once daily. Taking more than the recommended dose will not provide additional benefits and may increase the risk of side effects. Always follow the instructions provided by your doctor or the medication label.

Is it OK to take Allegra every day?

Allegra 120 is designed for daily use to provide continuous relief from allergy symptoms. However, it's essential to consult your doctor before taking Allegra 120 daily, especially if you have underlying medical conditions or take other medications.

Is Allegra safe for the liver?

Allegra 120 is generally considered safe for the liver when used as directed. However, patients with pre-existing liver disease or impairment should use caution and consult their doctor before taking Allegra 120.

Who should avoid Allegra?

Individuals with the following conditions should avoid Allegra 120 or consult their doctor before taking it:

• Severe renal impairment

• Hypersensitivity to Fexofenadine

• Pregnancy or breastfeeding (unless benefits outweigh risks)

• Concomitant use with certain medications (e.g., ketoconazole, erythromycin)

Is Allegra a steroid tablet?

No, Allegra 120 is not a steroid tablet. It's an antihistamine medication that works by blocking histamine receptors to provide relief from allergy symptoms.

Can I take Allegra at night?

Allegra 120 is designed for daytime use, as it's non-sedating. However, if you experience nighttime allergy symptoms, you can take Allegra 120 in the evening. Consult your doctor for personalized advice.

Does Allegra affect sleep?

Allegra 120 is generally considered non-sedating and should not affect sleep. However, individual reactions may vary. If you experience any sleep-related issues while taking Allegra 120, consult your doctor.

Which is the best tablet for allergy?

The best tablet for allergy depends on individual needs and preferences. Popular options include:

• Allegra 120

• Cetirizine

• Loratadine

• Diphenhydramine

Consult your doctor to determine the most suitable option for your specific allergy needs.

Why am I suddenly allergic to the sun?

Sun allergy, also known as solar urticaria or photodermatitis, can occur due to various factors, including:

• Genetic predisposition

• Medication reactions

• Skin conditions (e.g., eczema, psoriasis)

• Environmental factors (e.g., UV radiation, pollution)

Consult a dermatologist or healthcare professional for proper diagnosis and treatment.

Which medicine is best for allergies?

The best medicine for allergies depends on individual needs, severity of symptoms, and type of allergy. Popular over-the-counter (OTC) and prescription options include:

• Antihistamines (e.g., Allegra 120, cetirizine)

• Decongestants (e.g., pseudoephedrine)

• Nasal sprays (e.g., fluticasone)

• Immunotherapy (allergy shots)

Consult your doctor to determine the most suitable treatment plan for your specific allergy needs.

Is Allegra 120 good for throat infection?

Allegra 120 is primarily used to treat allergy symptoms. While it may provide some relief from throat congestion or itchiness associated with allergies, it's not a primary treatment for throat infections. If you have a persistent or severe throat infection, consult your doctor for proper diagnosis and treatment.

How quickly does Allegra work?

Allegra 120 typically starts working within 1-2 hours of administration, with peak effects observed within 4-6 hours. The duration of action is approximately 24 hours.

What are the drawbacks of Allegra?

Common drawbacks of Allegra 120 include:

• Headache

• Drowsiness (rare)

• Fatigue

• Dry mouth

• Cough

• Nausea

• Diarrhea

• Stomach upset

Rare but serious side effects may include:

• Anaphylaxis

• Angioedema

What is the strongest allergy medicine?

The strongest allergy medicine depends on individual needs and the type of allergy. Some popular options include:

1. Corticosteroids (e.g., prednisone)

2. Immunotherapy (allergy shots)

3. Sublingual immunotherapy (SLIT)

4. Antihistamines (e.g., diphenhydramine, chlorpheniramine)

Is Allegra better than cetirizine?

Both Allegra 120 and cetirizine are effective antihistamines. However, Allegra 120 is considered non-sedating, whereas cetirizine can cause drowsiness in some individuals. Allegra 120 also has a longer duration of action, providing relief for up to 24 hours.

Is allegra 120 a steroid?

No, Allegra 120 is not a steroid. It's an antihistamine medication that works by blocking histamine receptors to provide relief from allergy symptoms.

Is Allegra a safe drug?

Allegra 120 is generally considered safe when used as directed. However, as with any medication, it can cause side effects, and some individuals may be more susceptible to adverse effects. Always follow the instructions provided by your doctor or the medication label, and report any concerns or side effects to your doctor.

What other brands of Allegra 120 (Fexofenadine) available in the market:

1. Fexofenadine by Dr. Reddy's Laboratories

2. Allefree by Cipla Ltd.

3. Fexodin by Sun Pharmaceutical Industries Ltd.

4. Fexona by Glenmark Pharmaceuticals Ltd.

5. Fexotab by Torrent Pharmaceuticals Ltd.

6. Altiva by Ranbaxy Laboratories Ltd.

7. Fexofen by Lupin Ltd.

8. Fexolife by Cadila Pharmaceuticals Ltd.

9. Fexoquit by Zydus Cadila Healthcare Ltd.

10. Fexoriv by Micro Labs Ltd.